Washington D.C, Sept 26: If you want to get rid
of the alcohol addiction, then this is for you. A recent study has found
that diabetes medication can be used to treat alcohol dependence.A new
study on mice and rats at Sahlgrenska Academy shows that a medication
used for diabetes and obesity also could be a valuable tool for the
treatment of alcohol dependence.
The University of Gothenburg study shows that interfering with the hormone GLP-1 could be a target for treating alcohol dependence, which is an entirely novel aspect.Researchers found that a medication that resemble GLP-1, which is used to treat type 2 diabetes as well as obesity, also could be used to treat alcohol dependence.Usually, dopamine is released in the brain’s reward center in response to drinking alcohol, which leads to a sense of euphoria. The GLP-1-like substance prevents the ability of alcohol to increase dopamine in reward areas in the mice, suggesting that they no longer experience a reward from alcohol.
In addition, the diabetes medication caused the rats to decreases
their alcohol intake, as well as reduced the motivation to drink alcohol
in rats that were bred to drink a lot of alcohol. The medication also
prevents relapse drinking in rats, which is major problem for alcohol
dependent individuals.The GLP-1-like substance reduced the alcohol
consumption by 30-40 percent in rats that drank large quantities of
alcohol for several months, says researcher Elisabet Jerlhag.The study
is published in Addiction Biology.
The University of Gothenburg study shows that interfering with the hormone GLP-1 could be a target for treating alcohol dependence, which is an entirely novel aspect.Researchers found that a medication that resemble GLP-1, which is used to treat type 2 diabetes as well as obesity, also could be used to treat alcohol dependence.Usually, dopamine is released in the brain’s reward center in response to drinking alcohol, which leads to a sense of euphoria. The GLP-1-like substance prevents the ability of alcohol to increase dopamine in reward areas in the mice, suggesting that they no longer experience a reward from alcohol.
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